STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_14977Peptidase C13 family protein. (465 aa)    
Predicted Functional Partners:
NECAME_16641
Papain family cysteine protease; Belongs to the peptidase C1 family.
   
 
 0.582
NECAME_07678
Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]
      
 0.566
NECAME_14336
Papain family cysteine protease; Belongs to the peptidase C1 family.
   
 
 0.553
NECAME_14048
Papain family cysteine protease; Belongs to the peptidase C1 family.
   
 
 0.553
NECAME_12455
Papain family cysteine protease; Belongs to the peptidase C1 family.
   
 
 0.553
NECAME_02743
Papain family cysteine protease; Belongs to the peptidase C1 family.
   
 
 0.553
NECAME_02725
Papain family cysteine protease; Belongs to the peptidase C1 family.
   
 
 0.553
NECAME_02726
Papain family cysteine protease; Belongs to the peptidase C1 family.
   
 
 0.553
NECAME_11137
Cystatin domain protein.
    
 
 0.551
NECAME_11136
Cystatin domain protein.
    
 
 0.551
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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