STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_01067Homogentisate 1,2-dioxygenase. (571 aa)    
Predicted Functional Partners:
NECAME_08886
4-hydroxyphenylpyruvate dioxygenase.
  
 0.996
NECAME_00579
4-hydroxyphenylpyruvate dioxygenase.
  
 0.994
NECAME_01510
Putative maleylacetoacetate isomerase; Belongs to the GST superfamily.
  
 
 0.981
NECAME_19255
Uncharacterized protein.
  
 
 0.735
NECAME_01821
Fumarylacetoacetase.
 
 
 0.723
NECAME_18670
Fumarylacetoacetase.
  
 
 0.715
NECAME_18778
Fumarylacetoacetase.
  
 
 0.715
NECAME_04148
Phenylalanine-4-hydroxylase.
  
  
 0.704
NECAME_10138
Uncharacterized protein.
  
  
 0.704
NECAME_08210
Putative tryptophan 5-hydroxylase 1.
  
  
 0.704
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.