STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_1259426S proteasome subunit P45 family protein; Belongs to the AAA ATPase family. (433 aa)    
Predicted Functional Partners:
NECAME_13407
26S proteasome subunit P45 family protein; Belongs to the AAA ATPase family.
  
0.999
NECAME_03839
Ribosomal protein L13; Belongs to the mitochondrial carrier (TC 2.A.29) family.
  
0.999
NECAME_00440
PCI domain protein.
   
 0.999
NECAME_11128
ATPase, AAA family; Belongs to the AAA ATPase family.
  
0.999
NECAME_10321
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 0.999
NECAME_19668
Uncharacterized protein.
   
 0.999
NECAME_07553
ATPase, AAA family; Belongs to the AAA ATPase family.
  
0.999
NECAME_01685
26S proteasome non-ATPase regulatory subunit 7 family protein.
   
 0.999
NECAME_06456
Mov34/MPN/PAD-1 family protein.
   
 0.999
NECAME_14338
Ubiquitin carboxyl-terminal hydrolase.
   
 0.998
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.