NECAME_19687 protein (Necator americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NECAME_19687

HEAT repeat protein. (888 aa)

Predicted Functional Partners:

NECAME_16688

0.996

NECAME_03527

0.991

NECAME_05961

0.970

NECAME_14200

0.945

NECAME_03700

0.939

NECAME_07732

0.939

NECAME_05421

0.920

NECAME_09939

0.917

NECAME_06721

0.913

NECAME_03526

0.902

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_03526	NECAME_05421	W2T2L7	W2SJC3	Putative rRNA pseudouridine synthase.	Uncharacterized protein.	0.430
NECAME_03526	NECAME_19687	W2T2L7	W2T1K6	Putative rRNA pseudouridine synthase.	HEAT repeat protein.	0.902
NECAME_03527	NECAME_03700	W2T3M3	W2T1E1	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Importin subunit alpha; Belongs to the importin alpha family.	0.789
NECAME_03527	NECAME_05421	W2T3M3	W2SJC3	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Uncharacterized protein.	0.994
NECAME_03527	NECAME_06721	W2T3M3	W2TUQ5	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Uncharacterized protein.	0.474
NECAME_03527	NECAME_07732	W2T3M3	W2TMG4	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Uncharacterized protein.	0.789
NECAME_03527	NECAME_09939	W2T3M3	W2TC47	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Uncharacterized protein.	0.541
NECAME_03527	NECAME_14200	W2T3M3	W2SPM2	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Importin subunit alpha; Belongs to the importin alpha family.	0.799
NECAME_03527	NECAME_16688	W2T3M3	W2TXE4	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Nsp1-like region.	0.976
NECAME_03527	NECAME_19687	W2T3M3	W2T1K6	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	HEAT repeat protein.	0.991
NECAME_03700	NECAME_03527	W2T1E1	W2T3M3	Importin subunit alpha; Belongs to the importin alpha family.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.789
NECAME_03700	NECAME_05421	W2T1E1	W2SJC3	Importin subunit alpha; Belongs to the importin alpha family.	Uncharacterized protein.	0.755
NECAME_03700	NECAME_05961	W2T1E1	W2TXR2	Importin subunit alpha; Belongs to the importin alpha family.	Uncharacterized protein.	0.541
NECAME_03700	NECAME_16688	W2T1E1	W2TXE4	Importin subunit alpha; Belongs to the importin alpha family.	Nsp1-like region.	0.670
NECAME_03700	NECAME_19687	W2T1E1	W2T1K6	Importin subunit alpha; Belongs to the importin alpha family.	HEAT repeat protein.	0.939
NECAME_05421	NECAME_03526	W2SJC3	W2T2L7	Uncharacterized protein.	Putative rRNA pseudouridine synthase.	0.430
NECAME_05421	NECAME_03527	W2SJC3	W2T3M3	Uncharacterized protein.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.994
NECAME_05421	NECAME_03700	W2SJC3	W2T1E1	Uncharacterized protein.	Importin subunit alpha; Belongs to the importin alpha family.	0.755
NECAME_05421	NECAME_05961	W2SJC3	W2TXR2	Uncharacterized protein.	Uncharacterized protein.	0.916
NECAME_05421	NECAME_06721	W2SJC3	W2TUQ5	Uncharacterized protein.	Uncharacterized protein.	0.913