STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_03587Ephrin; Belongs to the ephrin family. (161 aa)    
Predicted Functional Partners:
NECAME_15160
Protein kinase domain-containing protein.
   
 0.751
NECAME_15159
Ephrin receptor ligand binding domain protein.
   
 0.751
NECAME_01485
Uncharacterized protein.
    
 0.627
NECAME_05893
Uncharacterized protein.
   
 0.626
NECAME_04841
GIT domain-containing protein.
     
 0.554
NECAME_01175
SH3 domain protein.
     
 0.511
NECAME_09145
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
     
 0.456
NECAME_08560
Tyrosine-protein kinase.
    
 0.421
NECAME_07204
Tyrosine-protein kinase.
    
 0.421
NECAME_15901
Kinase domain protein.
   
    0.414
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.