STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_03630Type IIB DNA topoisomerase. (237 aa)    
Predicted Functional Partners:
NECAME_06612
WD domain, G-beta repeat protein.
    
 
 0.908
NECAME_07240
Meiotic recombinase Dmc1; Belongs to the RecA family.
    
 0.865
NECAME_08781
Uncharacterized protein; Belongs to the RecA family.
    
 0.812
NECAME_01737
ERCC4 domain protein.
    
 
 0.796
NECAME_08628
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.743
NECAME_07971
MutS domain V protein.
   
 
 0.695
NECAME_08758
Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family.
    
 
 0.684
NECAME_00778
HORMA domain protein.
   
  
 0.676
NECAME_13027
Uncharacterized protein.
    
 0.668
NECAME_10785
Kinase, PfkB family.
      
 0.662
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.