STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_08239Gaa1-like, GPI transamidase component. (462 aa)    
Predicted Functional Partners:
NECAME_04345
Uncharacterized protein.
   
 0.999
NECAME_03475
Gpi16 subunit, GPI transamidase component.
   
 0.999
NECAME_16988
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
    
 0.999
NECAME_08231
GPI transamidase subunit PIG-U.
   
 0.998
NECAME_06073
Uncharacterized protein.
   
 0.965
NECAME_05372
GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
    
 0.964
NECAME_07470
GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.
   
 
 0.706
NECAME_12699
G domain-containing protein.
      
 0.686
NECAME_12329
Mannosyltransferase.
    
 
 0.673
NECAME_08562
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase domain protein.
      
 0.665
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.