STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_16422Glucose-6-phosphate isomerase; Belongs to the GPI family. (413 aa)    
Predicted Functional Partners:
NECAME_15129
Triosephosphate isomerase.
  
 0.999
NECAME_08877
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II.
  
 0.999
NECAME_05410
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
  
 
 0.998
NECAME_09088
Phosphopyruvate hydratase.
  
 0.997
NECAME_01086
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
  
 0.996
NECAME_10328
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.995
NECAME_00137
Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family.
   
 
 0.994
NECAME_05134
ADP-specific Phosphofructokinase/Glucokinase conserved region.
    
 0.993
NECAME_15576
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Belongs to the phosphohexose mutase family.
  
 
 0.992
NECAME_12925
Phosphomannose isomerase type I.
  
 
 0.992
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.