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iscR protein (Alcaligenes faecalis) - STRING interaction network
"iscR" - Fe-S cluster assembly transcriptional regulator IscR in Alcaligenes faecalis
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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iscRFe-S cluster assembly transcriptional regulator IscR; Derived by automated computational analysis using gene prediction method- Protein Homology (158 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily (397 aa)
 
   
  0.990
JT27_01535
Scaffolding protein; Derived by automated computational analysis using gene prediction method- Protein Homology (127 aa)
   
   
  0.945
iscA
Iron-sulfur cluster assembly protein IscA; Forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the HesB/IscA family (107 aa)
   
 
  0.841
AFA_08795
Iron-sulfur cluster assembly scaffold protein; Derived by automated computational analysis using gene prediction method- Protein Homology (150 aa)
 
   
  0.741
JT27_01550
Protein tyrosine phosphatase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family (163 aa)
         
  0.704
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (219 aa)
         
  0.683
erpA
Putative iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters (122 aa)
   
 
  0.655
JT27_01525
Methylglyoxal synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (292 aa)
              0.590
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (360 aa)
           
  0.579
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (673 aa)
         
  0.545
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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