STRINGSTRING
murJ protein (Alcaligenes faecalis) - STRING interaction network
"murJ" - Probable lipid II flippase MurJ in Alcaligenes faecalis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
murJProbable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane (517 aa)    
Predicted Functional Partners:
JT27_01930
3-hydroxy-2-methylbutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family (254 aa)
              0.800
JT27_09145
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins (456 aa)
 
   
  0.784
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA (87 aa)
              0.783
JT27_01765
Riboflavin biosynthesis protein; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ribF family (321 aa)
 
        0.764
cysS
Cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family (483 aa)
            0.728
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family (218 aa)
              0.693
yidC
Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (555 aa)
   
        0.689
mrdB
Peptidoglycan glycosyltransferase MrdB; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily (380 aa)
   
   
  0.668
ftsW
Probable peptidoglycan glycosyltransferase FtsW; Peptidoglycan polymerase that is essential for cell division; Belongs to the SEDS family. FtsW subfamily (397 aa)
   
   
  0.645
dnaQ
DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3’-5’ exonuclease (241 aa)
 
     
  0.591
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
Server load: low (9%) [HD]