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dtd protein (Alcaligenes faecalis) - STRING interaction network
"dtd" - D-aminoacyl-tRNA deacylase in Alcaligenes faecalis
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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dtdD-aminoacyl-tRNA deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl- tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality; Belongs to the DTD family (152 aa)    
Predicted Functional Partners:
JT27_02270
Membrane protein; Derived by automated computational analysis using gene prediction method- Protein Homology (172 aa)
         
  0.822
JT27_02275
Transporter; Derived by automated computational analysis using gene prediction method- Protein Homology (114 aa)
              0.810
JT27_02260
UPF0225 protein JT27_02260; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the UPF0225 family (133 aa)
              0.710
JT27_02265
GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (156 aa)
              0.690
lpxH
UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (266 aa)
 
     
  0.613
nhaA
Na(+)/H(+) antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons (454 aa)
              0.546
tyrS
Tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily (408 aa)
   
   
  0.466
JT27_01435
Competence protein ComEC; Derived by automated computational analysis using gene prediction method- Protein Homology (822 aa)
         
  0.416
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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