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trpE protein (Alcaligenes faecalis) - STRING interaction network
"trpE" - Anthranilate synthase component 1 in Alcaligenes faecalis
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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trpEAnthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (506 aa)    
Predicted Functional Partners:
JT27_02870
Anthranilate synthase component II; TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method- Protein Homology (187 aa)
  0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5’-phosphoribosyl)-anthranilate (PRA) (344 aa)
 
  0.999
JT27_17220
Chorismate mutase; Derived by automated computational analysis using gene prediction method- Protein Homology (363 aa)
 
 
  0.980
trpC
Indole-3-glycerol phosphate synthase; Involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the TrpC family (266 aa)
 
  0.978
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate; Belongs to the TrpA family (277 aa)
 
 
  0.968
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system (353 aa)
 
 
  0.946
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (399 aa)
 
   
  0.945
JT27_08180
Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the TrpC family (263 aa)
 
  0.922
trpF
N-(5’-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the TrpF family (220 aa)
 
   
  0.880
JT27_02800
Isochorismate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (401 aa)
   
 
0.840
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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