STRINGSTRING
def protein (Alcaligenes faecalis) - STRING interaction network
"def" - Peptide deformylase in Alcaligenes faecalis
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (172 aa)    
Predicted Functional Partners:
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus (313 aa)
 
  0.996
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (119 aa)
 
 
  0.971
rpsU
30S ribosomal protein S21; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the bacterial ribosomal protein bS21 family (70 aa)
     
      0.951
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (257 aa)
   
 
  0.951
rpsE
30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; Belongs to the universal ribosomal protein uS5 family (173 aa)
   
 
  0.950
rplR
50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (117 aa)
   
 
      0.950
rpsI
30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the universal ribosomal protein uS9 family (130 aa)
   
 
  0.950
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (123 aa)
     
 
  0.949
rpmI
50S ribosomal protein L35; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the bacterial ribosomal protein bL35 family (65 aa)
   
      0.948
rplQ
50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method- Protein Homology (128 aa)
     
      0.947
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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