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JT27_03085 protein (Alcaligenes faecalis) - STRING interaction network
"JT27_03085" - Hydroxymethylglutaryl-CoA lyase in Alcaligenes faecalis
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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JT27_03085Hydroxymethylglutaryl-CoA lyase; Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA; Derived by automated computational analysis using gene prediction method- Protein Homology (306 aa)    
Predicted Functional Partners:
JT27_07015
Acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method- Protein Homology (397 aa)
   
 
  0.910
JT27_16435
Succinyl-CoA-3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method- Protein Homology (217 aa)
   
 
  0.909
JT27_16430
Succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method- Protein Homology (232 aa)
       
  0.905
JT27_15890
3-hydroxybutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family (260 aa)
     
 
    0.902
JT27_03090
Membrane protein; Derived by automated computational analysis using gene prediction method- Protein Homology (155 aa)
              0.850
JT27_04610
Methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method- Protein Homology (535 aa)
 
  0.849
sucC
Succinate--CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (386 aa)
     
  0.830
sucD
Succinate--CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit (293 aa)
     
  0.830
JT27_03455
Hydroxymethylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family (301 aa)
   
   
 
0.826
gltA
Citrate synthase; Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the citrate [...] (434 aa)
   
 
  0.817
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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