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cysG protein (Alcaligenes faecalis) - STRING interaction network
"cysG" - Siroheme synthase in Alcaligenes faecalis
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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cysGSiroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme (484 aa)    
Predicted Functional Partners:
cysI
Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family (569 aa)
 
 
  0.993
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps; Belongs to the HMBS family (320 aa)
   
  0.987
JT27_17760
Uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (266 aa)
   
 
  0.977
JT27_05885
Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component (610 aa)
   
  0.976
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (358 aa)
   
 
  0.968
JT27_15575
Siroheme synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (326 aa)
 
 
0.919
JT27_17755
Uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (452 aa)
     
 
  0.914
JT27_06090
Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family (339 aa)
 
 
  0.908
JT27_20115
Rieske (2Fe-2S) protein; Derived by automated computational analysis using gene prediction method- Protein Homology (104 aa)
   
   
  0.895
JT27_14505
3-phenylpropionate dioxygenase; Derived by automated computational analysis using gene prediction method- Protein Homology (106 aa)
   
   
  0.895
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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