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ubiA protein (Alcaligenes faecalis) - STRING interaction network
"ubiA" - 4-hydroxybenzoate octaprenyltransferase in Alcaligenes faecalis
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ubiA4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate (314 aa)    
Predicted Functional Partners:
ubiD
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis; Belongs to the UbiD family (514 aa)
 
 
  0.980
ubiX
Flavin prenyltransferase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN (183 aa)
 
 
  0.977
ubiC
Probable chorismate pyruvate-lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family (191 aa)
   
 
  0.964
JT27_08270
Octaprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the FPP/GGPP synthase family (321 aa)
 
 
  0.946
JT27_05000
4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method- Protein Homology (147 aa)
         
  0.912
ubiG
Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family (240 aa)
 
 
  0.865
JT27_13940
Monooxygenase; Derived by automated computational analysis using gene prediction method- Protein Homology (386 aa)
   
   
  0.824
JT27_16420
Electron transfer flavoprotein-ubiquinone oxidoreductase; Derived by automated computational analysis using gene prediction method- Protein Homology (548 aa)
 
   
  0.765
hemF
Oxygen-dependent coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX (301 aa)
 
   
  0.719
JT27_06445
Membrane protein; Derived by automated computational analysis using gene prediction method- Protein Homology (419 aa)
   
        0.709
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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