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glmU protein (Alcaligenes faecalis) - STRING interaction network
"glmU" - Bifunctional protein GlmU in Alcaligenes faecalis
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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glmUBifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (456 aa)    
Predicted Functional Partners:
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family (447 aa)
 
  0.989
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily (420 aa)
 
  0.970
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily (316 aa)
   
  0.940
glmS
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (608 aa)
 
  0.925
JT27_07185
UDP-N-acetylglucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family (373 aa)
   
 
  0.919
JT27_11790
Vi polysaccharide biosynthesis protein VipB/TviC; Derived by automated computational analysis using gene prediction method- Protein Homology (341 aa)
   
 
  0.908
lpxA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (262 aa)
   
 
  0.907
JT27_10710
Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (348 aa)
     
 
  0.905
JT27_06555
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (290 aa)
              0.763
JT27_03010
UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (276 aa)
   
   
  0.724
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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