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acnA protein (Alcaligenes faecalis) - STRING interaction network
"acnA" - Aconitate hydratase in Alcaligenes faecalis
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (917 aa)    
Predicted Functional Partners:
gltA
Citrate synthase; Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the citrate [...] (434 aa)
 
  0.975
JT27_14900
Isocitrate dehydrogenase [NADP]; Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method- Protein Homology (418 aa)
 
  0.944
AFA_11795
Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method- Protein Homology (435 aa)
     
 
  0.915
JT27_09595
Aconitate hydratase B; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the aconitase/IPM isomerase family (861 aa)
   
  0.855
JT27_02385
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (884 aa)
   
   
 
0.809
JT27_09580
Citrate synthase; Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method- Protein Homology (387 aa)
 
  0.755
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily (465 aa)
   
   
  0.752
JT27_13325
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family (788 aa)
   
   
  0.740
JT27_10645
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)- malate; Belongs to the class-I fumarase family (506 aa)
   
   
  0.671
JT27_16710
Quinone oxidoreductase; Derived by automated computational analysis using gene prediction method- Protein Homology (328 aa)
       
 
  0.608
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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