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mpl protein (Alcaligenes faecalis) - STRING interaction network
"mpl" - UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase in Alcaligenes faecalis
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
mplUDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate; Belongs to the MurCDEF family. Mpl subfamily (454 aa)    
Predicted Functional Partners:
JT27_08555
Esterase; Derived by automated computational analysis using gene prediction method- Protein Homology (195 aa)
              0.845
JT27_01460
Single-stranded DNA exonuclease; Derived by automated computational analysis using gene prediction method- Protein Homology (569 aa)
 
  0.823
JT27_08550
Ribonuclease II; Derived by automated computational analysis using gene prediction method- Protein Homology (629 aa)
              0.769
JT27_08545
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (289 aa)
              0.769
JT27_08565
Thioredoxin; Derived by automated computational analysis using gene prediction method- Protein Homology (165 aa)
              0.740
murE
Multifunctional fusion protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily (925 aa)
 
 
0.736
aroE
Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) (283 aa)
   
   
  0.674
ftsI
Peptidoglycan D,D-transpeptidase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily (579 aa)
 
  0.645
mtgA
Biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family (235 aa)
   
   
  0.622
ddl
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family (316 aa)
 
  0.614
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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