Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method- Protein Homology (121 aa)
Predicted Functional Partners:
3-beta hydroxysteroid dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology (203 aa)
Membrane protein; Derived by automated computational analysis using gene prediction method- Protein Homology (159 aa)
Amino acid transporter; Derived by automated computational analysis using gene prediction method- Protein Homology (205 aa)
FMN-dependent NADH-azoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (208 aa)