STRINGSTRING
JT27_13010 protein (Alcaligenes faecalis) - STRING interaction network
"JT27_13010" - ATP-dependent endonuclease in Alcaligenes faecalis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JT27_13010ATP-dependent endonuclease; Derived by automated computational analysis using gene prediction method- Protein Homology (582 aa)    
Predicted Functional Partners:
JT27_13015
DNA helicase; Derived by automated computational analysis using gene prediction method- Protein Homology (579 aa)
 
 
  0.986
JT27_12600
Metallophosphatase; Derived by automated computational analysis using gene prediction method- Protein Homology (372 aa)
   
 
  0.944
rep
ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3’ to 5’ direction (691 aa)
   
 
  0.787
JT27_01745
DNA helicase; Derived by automated computational analysis using gene prediction method- Protein Homology (764 aa)
   
 
  0.787
JT27_05545
Type I restriction enzyme R Protein; Subunit R is required for both nuclease and ATPase activities, but not for modification (1049 aa)
   
        0.780
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (905 aa)
   
 
  0.759
JT27_10425
Nuclease; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the helicase family. UvrD subfamily (1100 aa)
   
   
  0.717
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (623 aa)
   
 
  0.663
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5’-phosphoryl and 3’-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily (695 aa)
         
  0.656
JT27_00470
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (1106 aa)
   
 
  0.643
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
Server load: low (10%) [HD]