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purA protein (Alcaligenes faecalis) - STRING interaction network
"purA" - Adenylosuccinate synthetase in Alcaligenes faecalis
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (431 aa)    
Predicted Functional Partners:
purH
Bifunctional purine biosynthesis protein PurH; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (530 aa)
 
  0.988
JT27_16895
Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines- the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily (458 aa)
 
 
  0.987
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (486 aa)
 
 
  0.987
JT27_17860
Aspartate carbamoyltransferase; Catalyzes the conversion of carbamoyl phosphate and aspartate to form N-carbamoyl aspartate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ATCase/OTCase family (431 aa)
 
 
  0.961
argG
Argininosuccinate synthase; Catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the argininosuccinate synthase family. Type 2 subfamily (444 aa)
   
 
  0.949
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (528 aa)
 
   
  0.921
JT27_03175
L-asparaginase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the asparaginase 1 family (329 aa)
   
  0.912
surE
5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family (246 aa)
   
 
    0.909
aspA
Aspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method- Protein Homology (472 aa)
         
  0.906
JT27_05040
5’-nucleotidase; Derived by automated computational analysis using gene prediction method- Protein Homology (333 aa)
     
 
  0.905
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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