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JT27_15575 protein (Alcaligenes faecalis) - STRING interaction network
"JT27_15575" - Siroheme synthase in Alcaligenes faecalis
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
JT27_15575Siroheme synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (326 aa)    
Predicted Functional Partners:
JT27_17760
Uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (266 aa)
   
 
  0.923
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme (484 aa)
 
 
0.919
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (358 aa)
   
 
  0.915
JT27_17755
Uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (452 aa)
     
 
  0.904
JT27_15570
Derived by automated computational analysis using gene prediction method- Protein Homology (107 aa)
              0.682
JT27_15565
Derived by automated computational analysis using gene prediction method- Protein Homology (515 aa)
         
  0.623
hemL
Glutamate-1-semialdehyde 2,1-aminomutase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method- Protein Homology (427 aa)
   
  0.608
cysI
Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family (569 aa)
 
 
  0.466
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps; Belongs to the HMBS family (320 aa)
 
   
  0.426
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Alcaligenes faecalis, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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