Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Glutamyl-tRNA amidotransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (153 aa)
Predicted Functional Partners:
Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method- Protein Homology (139 aa)
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family (388 aa)
Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase (1065 aa)
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (427 aa)
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (245 aa)
DTW domain-containing protein; Derived by automated computational analysis using gene prediction method- Protein Homology (204 aa)
30S ribosomal protein S21; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the bacterial ribosomal protein bS21 family (70 aa)
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (740 aa)
tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family (352 aa)
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication; Belongs to the DnaG primase family (668 aa)