STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
easGAgroclavine dehydrogenase; Agroclavine dehydrogenase; part of the gene cluster that mediates the biosynthesis of fungal ergot alkaloid. DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4- dimethylallyl-L-tryptophan. The second step is catalyzed by the methyltransferase easF that methylates 4- dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (By similarity). The catalase easC and the FAD-dependent oxidoreductase easE then transfor [...] (290 aa)    
Predicted Functional Partners:
CPUR_04192
Probable NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mitochondrial; Belongs to the complex I 30 kDa subunit family.
   
 0.896
CPUR_06874
CI-23 NADH-ubiquinone oxidoreductase 23 kDa subunit.
   
 0.890
CPUR_07274
Probable NADH dehydrogenase (Ubiquinone) 49K chain; Belongs to the complex I 49 kDa subunit family.
   
 0.890
CPUR_04641
Probable NADH dehydrogenase (Ubiquinone) 22K chain.
   
 0.889
CPUR_03048
Probable NADH-ubiquinone oxidoreductase 19.3 kDa subunit, mitochondrial; Belongs to the complex I 20 kDa subunit family.
   
 0.881
CPUR_06966
Probable NADH dehydrogenase (Ubiquinone) 78K chain; Belongs to the complex I 75 kDa subunit family.
   
 0.880
CPUR_05109
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 0.875
CPUR_05281
Probable NADH-ubiquinone oxidoreductase.
   
 0.871
CPUR_06891
Related to NADH-ubiquinone oxidoreductase B16.6 subunit.
   
 0.871
CPUR_07441
NUO-10.5 NADH2 dehydrogenase (Ubiquinone) 10.5K chain.
   
 0.867
Your Current Organism:
Claviceps purpurea
NCBI taxonomy Id: 1111077
Other names: C. purpurea 20.1, Claviceps purpurea 20.1
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