STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yaaXDUF2502 family putative periplasmic protein; To E.coli YpeC (98 aa)    
Predicted Functional Partners:
yagH
CP4-6 prophage; putative xylosidase/arabinosidase; Putative beta-xylosidase
      
 0.790
cybB
Superoxide oxidase; B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm
  
   
 0.739
yebO
annotation not available
  
     0.709
mzrA
Modulator of envz/ompr regulon; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. Links the two-component systems CpxA/CpxR and EnvZ/OmpR
  
     0.686
yodB
Cytochrome b561 homolog; Belongs to the cytochrome b561 family
      
 0.678
flk
Putative flagella assembly protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion (T3S) system. Plays a role in hindering to flip the flagellar T3S specificity switch from the rod and hook-type substrates to filament-type substrates prior to hook-basal body (HBB) completion possibly by preventing interaction of FliK with FlhB (By similarity)
  
     0.670
ybjO
annotation not available
  
     0.659
yidX
Putative lipoprotein yidx; Uncharacterized protein YidX; Putative replicase EC 2.7.-
  
     0.645
mcbA
Mqsr-controlled colanic acid and biofilm protein a; Affects biofilm formation and mucoidy
  
     0.617
yaaA
Peroxide resistance protein, lowers intracellular iron; Involved in the cellular response to hydrogen peroxide (H(2)O(2)) stress. During H(2)O(2) stress, prevents oxidative damage to both DNA and proteins by diminishing the amount of unincorporated iron within the cell
      
 0.605
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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