STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yaaWUPF0174 family protein; Belongs to the UPF0174 family. (237 aa)    
Predicted Functional Partners:
yaaI
UPF0412 family protein; Belongs to the UPF0412 family.
  
  
 0.949
yghW
DUF2623 family protein.
   
  
 0.820
yfcH
Putative sugar nucleotide epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.
    
 
 0.815
yegV
Putative kinase; Belongs to the carbohydrate kinase PfkB family.
      
 0.805
satP
Succinate-acetate transporter; Uptake of acetate and succinate. Transport is energetically dependent on the protonmotive force.
  
  
 0.774
ydhS
Putative oxidoreductase.
      
 0.644
yaaU
Putative MFS sugar transporter; Putative transport protein.
   
  
 0.548
rhmA
2-keto-3-deoxy-L-rhamnonate aldolase; Catalyzes the reversible retro-aldol cleavage of 2-keto-3- deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde. 2-keto-3-deoxy- L-mannonate, 2-keto-3-deoxy-L-lyxonate and 4-hydroxy-2-ketoheptane-1,7- dioate (HKHD) are also reasonably good substrates, although 2-keto-3- deoxy-L-rhamnonate is likely to be the physiological substrate.
      
 0.544
caiA
Crotonobetaine reductase subunit II, FAD-binding; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA. The electron donor could be the FixA/FixB complex.
   
  
 0.538
fixC
Putative oxidoreductase; Could be part of an electron transfer system required for anaerobic carnitine reduction; Belongs to the ETF-QO/FixC family.
   
  
 0.533
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.