close STRING Database User Survey
Please help us improve further — take a moment to fill our brief user survey.
 
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fixBElectron transfer flavoprotein alpha subunit; Required for anaerobic carnitine reduction. May bring reductant to CaiA (313 aa)    
Predicted Functional Partners:
fixA
Anaerobic carnitine reduction putative electron transfer flavoprotein subunit; Required for anaerobic carnitine reduction. May bring reductant to CaiA
 0.999
fixC
Electron transfer flavoprotein-quinone oxidoreductase; Could be part of an electron transfer system required for anaerobic carnitine reduction
 
  
 0.993
fixX
Putative 4fe-4s ferredoxin-type protein; Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster-containing protein
 
 
 0.992
ydiQ
Putative electron transfer flavoprotein subunit ydiq; May play a role in a redox process
 0.961
caiA
Crotonobetaine reductase subunit ii, fad-binding; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA . The electron donor could be the FixA/FixB complex
 
 0.958
ydiO
Putative acyl-coa dehydrogenase; Belongs to the acyl-CoA dehydrogenase family
 
 0.927
caiD
Crotonobetainyl-coa hydratase; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA
 
 0.880
ydiT
Putative 3fe-4s ferredoxin-type protein; Could be a 3Fe-4S cluster-containing protein. Probably participates in a redox process with YdiQ, YdiR and YdiS
 
 
 0.863
ygcR
Putative flavoprotein; May play a role in a redox process
 
 0.851
caiC
Putative crotonobetaine/carnitine-coa ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine
 
  
 0.849
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (8%) [HD]