STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fixCPutative oxidoreductase; Could be part of an electron transfer system required for anaerobic carnitine reduction; Belongs to the ETF-QO/FixC family. (428 aa)    
Predicted Functional Partners:
fixX
Putative 4Fe-4S ferredoxin-type protein; Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster-containing protein; Belongs to the bacterial-type ferredoxin family. FixX subfamily.
 
 
 0.996
fixB
Protein FixB; Required for anaerobic carnitine reduction. May bring reductant to CaiA; Belongs to the ETF alpha-subunit/FixB family.
 
 
 0.992
fixA
Anaerobic carnitine reduction putative electron transfer flavoprotein subunit; Required for anaerobic carnitine reduction. May bring reductant to CaiA; Belongs to the ETF beta-subunit/FixA family.
 
 
 0.988
yaaU
Putative MFS sugar transporter; Putative transport protein.
 
  
 0.929
ydiT
Putative 3Fe-4S ferredoxin-type protein; Could be a 3Fe-4S cluster-containing protein. Probably participates in a redox process with YdiQ, YdiR and YdiS.
 
 
 0.859
ygcO
Putative 4Fe-4S cluster-containing protein; Could be a 3Fe-4S cluster-containing protein. Probably participates in a redox process with YgcN, YgcQ and YgcR.
 
 
 0.858
caiA
Crotonobetaine reductase subunit II, FAD-binding; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA. The electron donor could be the FixA/FixB complex.
 
  
 0.855
ydiQ
Putative electron transfer flavoprotein subunit; May play a role in a redox process; Belongs to the ETF beta-subunit/FixA family.
 
 
 0.779
caiC
Putative crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.774
ydiR
Putative electron transfer flavoprotein, FAD-binding subunit; May play a role in a redox process; Belongs to the ETF alpha-subunit/FixB family.
 
 
 0.746
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.