node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
araA | araB | b0062 | b0063 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | 0.999 |
araA | araC | b0062 | b0064 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | Ara regulon transcriptional activator; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. Functions both as a positive and a negative regulator. In the presence of arabinose, activates the expression of the araBAD, araE, araFGH and araJ promoters. In the absence of arabinose, negatively regulates the araBAD operon. Represses its own transcription. Acts by binding directly to DNA. | 0.824 |
araA | araD | b0062 | b0061 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D- xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon- carbon bond cleavage analogous to a class II aldolase reaction). | 0.999 |
araA | araE | b0062 | b2841 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | 0.936 |
araA | rhaB | b0062 | b3904 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). It could also play a role in the metabolism of some rare sugars such as L-fructose. Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1- phosphate. Uridine triphosphate (UTP), cytidine 5-triphosphate (CTP), guanosine 5-triphosphate (GTP), and thymidine triphosphate (TTP) also can act as phosphoryl donors. It can also phosphorylate L-fuculose and L-xylulose. Belongs to the rhamnulokinase family. | 0.580 |
araA | rhaD | b0062 | b3902 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Also catalyzes the dephosphorylation of phospho- serine in vitro ; Belongs to the aldolase class II family. RhaD subfamily. | 0.628 |
araA | sgbE | b0062 | b3583 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | L-ribulose-5-phosphate 4-epimerase; Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction). May be involved in the utilization of 2,3-diketo-L-gulonate. | 0.992 |
araA | ulaF | b0062 | b4198 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | L-ribulose 5-phosphate 4-epimerase; Catalyzes the isomerization of L-ribulose 5-phosphate to D- xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization; Belongs to the aldolase class II family. AraD/FucA subfamily. | 0.992 |
araA | xylA | b0062 | b3565 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | D-xylose isomerase; Protein involved in carbohydrate catabolic process and glucose metabolic process; Belongs to the xylose isomerase family. | 0.936 |
araB | araA | b0063 | b0062 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | 0.999 |
araB | araC | b0063 | b0064 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | Ara regulon transcriptional activator; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. Functions both as a positive and a negative regulator. In the presence of arabinose, activates the expression of the araBAD, araE, araFGH and araJ promoters. In the absence of arabinose, negatively regulates the araBAD operon. Represses its own transcription. Acts by binding directly to DNA. | 0.932 |
araB | araD | b0063 | b0061 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D- xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon- carbon bond cleavage analogous to a class II aldolase reaction). | 0.999 |
araB | araE | b0063 | b2841 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | 0.958 |
araB | rhaB | b0063 | b3904 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). It could also play a role in the metabolism of some rare sugars such as L-fructose. Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1- phosphate. Uridine triphosphate (UTP), cytidine 5-triphosphate (CTP), guanosine 5-triphosphate (GTP), and thymidine triphosphate (TTP) also can act as phosphoryl donors. It can also phosphorylate L-fuculose and L-xylulose. Belongs to the rhamnulokinase family. | 0.965 |
araB | rhaD | b0063 | b3902 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Also catalyzes the dephosphorylation of phospho- serine in vitro ; Belongs to the aldolase class II family. RhaD subfamily. | 0.963 |
araB | rpe | b0063 | b3386 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | D-ribulose-5-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate. | 0.933 |
araB | sgbE | b0063 | b3583 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | L-ribulose-5-phosphate 4-epimerase; Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction). May be involved in the utilization of 2,3-diketo-L-gulonate. | 0.994 |
araB | ulaF | b0063 | b4198 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | L-ribulose 5-phosphate 4-epimerase; Catalyzes the isomerization of L-ribulose 5-phosphate to D- xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization; Belongs to the aldolase class II family. AraD/FucA subfamily. | 0.993 |
araB | xylA | b0063 | b3565 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | D-xylose isomerase; Protein involved in carbohydrate catabolic process and glucose metabolic process; Belongs to the xylose isomerase family. | 0.927 |
araC | araA | b0064 | b0062 | Ara regulon transcriptional activator; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. Functions both as a positive and a negative regulator. In the presence of arabinose, activates the expression of the araBAD, araE, araFGH and araJ promoters. In the absence of arabinose, negatively regulates the araBAD operon. Represses its own transcription. Acts by binding directly to DNA. | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | 0.824 |