node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ddlB | ftsI | b0092 | b0084 | D-alanine--d-alanine ligase b; Cell wall formation | Cell division protein ftsi (penicillin-binding protein 3); Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum Required for localization of FtsN | 0.923 |
ddlB | ftsQ | b0092 | b0093 | D-alanine--d-alanine ligase b; Cell wall formation | Divisome assembly protein, membrane anchored protein involved in growth of wall at septum; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly | 0.994 |
ddlB | ftsW | b0092 | b0089 | D-alanine--d-alanine ligase b; Cell wall formation | Putative lipid ii flippase ftsw; Peptidoglycan polymerase that is essential for cell division (Probable). Functions probably in conjunction with the penicillin- binding protein 3 (ftsI) . Required for localization of FtsI | 0.954 |
ddlB | mraY | b0092 | b0087 | D-alanine--d-alanine ligase b; Cell wall formation | Phospho-n-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan | 0.865 |
ddlB | murB | b0092 | b3972 | D-alanine--d-alanine ligase b; Cell wall formation | Udp-n-acetylenolpyruvoylglucosamine reductase, fad-binding; Cell wall formation | 0.925 |
ddlB | murC | b0092 | b0091 | D-alanine--d-alanine ligase b; Cell wall formation | Udp-n-acetylmuramate--l-alanine ligase; Cell wall formation | 0.998 |
ddlB | murD | b0092 | b0088 | D-alanine--d-alanine ligase b; Cell wall formation | Udp-n-acetylmuramoyl-l-alanine--d-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) | 0.984 |
ddlB | murE | b0092 | b0085 | D-alanine--d-alanine ligase b; Cell wall formation | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use many meso-diaminopimelate analogs as substrates, although much less efficiently, but not L-lysine | 0.981 |
ddlB | murF | b0092 | b0086 | D-alanine--d-alanine ligase b; Cell wall formation | Udp-n-acetylmuramoyl-tripeptide--d-alanyl-d-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein | 0.998 |
ddlB | murG | b0092 | b0090 | D-alanine--d-alanine ligase b; Cell wall formation | Udp-n-acetylglucosamine--n-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol n-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) | 0.979 |
ftsI | ddlB | b0084 | b0092 | Cell division protein ftsi (penicillin-binding protein 3); Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum Required for localization of FtsN | D-alanine--d-alanine ligase b; Cell wall formation | 0.923 |
ftsI | ftsQ | b0084 | b0093 | Cell division protein ftsi (penicillin-binding protein 3); Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum Required for localization of FtsN | Divisome assembly protein, membrane anchored protein involved in growth of wall at septum; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly | 0.999 |
ftsI | ftsW | b0084 | b0089 | Cell division protein ftsi (penicillin-binding protein 3); Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum Required for localization of FtsN | Putative lipid ii flippase ftsw; Peptidoglycan polymerase that is essential for cell division (Probable). Functions probably in conjunction with the penicillin- binding protein 3 (ftsI) . Required for localization of FtsI | 0.999 |
ftsI | mraY | b0084 | b0087 | Cell division protein ftsi (penicillin-binding protein 3); Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum Required for localization of FtsN | Phospho-n-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan | 0.986 |
ftsI | murB | b0084 | b3972 | Cell division protein ftsi (penicillin-binding protein 3); Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum Required for localization of FtsN | Udp-n-acetylenolpyruvoylglucosamine reductase, fad-binding; Cell wall formation | 0.750 |
ftsI | murC | b0084 | b0091 | Cell division protein ftsi (penicillin-binding protein 3); Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum Required for localization of FtsN | Udp-n-acetylmuramate--l-alanine ligase; Cell wall formation | 0.986 |
ftsI | murD | b0084 | b0088 | Cell division protein ftsi (penicillin-binding protein 3); Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum Required for localization of FtsN | Udp-n-acetylmuramoyl-l-alanine--d-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) | 0.993 |
ftsI | murE | b0084 | b0085 | Cell division protein ftsi (penicillin-binding protein 3); Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum Required for localization of FtsN | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use many meso-diaminopimelate analogs as substrates, although much less efficiently, but not L-lysine | 0.999 |
ftsI | murF | b0084 | b0086 | Cell division protein ftsi (penicillin-binding protein 3); Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum Required for localization of FtsN | Udp-n-acetylmuramoyl-tripeptide--d-alanyl-d-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein | 0.998 |
ftsI | murG | b0084 | b0090 | Cell division protein ftsi (penicillin-binding protein 3); Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum Required for localization of FtsN | Udp-n-acetylglucosamine--n-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol n-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) | 0.998 |