node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
adhE | can | b1241 | b0126 | Acetaldehyde dehydrogenase [acetylating]; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction; In the N-terminal section; belongs to the aldehyde dehydrogenase family. | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | 0.597 |
adhE | cynT | b1241 | b0339 | Acetaldehyde dehydrogenase [acetylating]; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction; In the N-terminal section; belongs to the aldehyde dehydrogenase family. | Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate. | 0.424 |
adhE | yadH | b1241 | b0128 | Acetaldehyde dehydrogenase [acetylating]; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction; In the N-terminal section; belongs to the aldehyde dehydrogenase family. | Putative ABC transporter permease. | 0.509 |
caiE | can | b0035 | b0126 | Stimulator of CaiD and CaiB enzyme activities; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | 0.551 |
caiE | cynT | b0035 | b0339 | Stimulator of CaiD and CaiB enzyme activities; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate. | 0.589 |
can | adhE | b0126 | b1241 | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | Acetaldehyde dehydrogenase [acetylating]; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction; In the N-terminal section; belongs to the aldehyde dehydrogenase family. | 0.597 |
can | caiE | b0126 | b0035 | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | Stimulator of CaiD and CaiB enzyme activities; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | 0.551 |
can | cynS | b0126 | b0340 | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | 0.964 |
can | cynT | b0126 | b0339 | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate. | 0.943 |
can | dauA | b0126 | b1206 | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | C4-dicarboxylic acid transporter; Responsible for the aerobic transport of succinate from the periplasm to the cytoplasm at acidic pH. Can transport other C4- dicarboxylic acids such as aspartate and fumarate. May also play a role in the regulation of C4-dicarboxylic acid metabolism at pH 7, via regulation of expression and/or activity of DctA. May act as a co- sensor of DcuS. | 0.888 |
can | glmS | b0126 | b3729 | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | L-glutamine:D-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.542 |
can | slyD | b0126 | b3349 | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | FKBP-type peptidyl prolyl cis-trans isomerase (rotamase); Folding helper with both chaperone and peptidyl-prolyl cis- trans isomerase (PPIase) activities. Chaperone activity prevents aggregation of unfolded or partially folded proteins and promotes their correct folding. PPIases catalyze the cis-trans isomerization of Xaa- Pro bonds of peptides, which accelerates slow steps of protein folding and thus shortens the lifetime of intermediates. Both strategies lower the concentration of intermediates and increase the productivity and yield of the folding reaction. SlyD could be involved in [...] | 0.700 |
can | yadG | b0126 | b0127 | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | Putative ABC transporter ATPase; Putative ATP-binding component of a transport system. | 0.638 |
can | yadH | b0126 | b0128 | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | Putative ABC transporter permease. | 0.567 |
can | yrdA | b0126 | b3279 | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | Bacterial transferase hexapeptide domain protein; Putative transferase; Belongs to the gamma-class carbonic anhydrase family. | 0.549 |
cynS | can | b0340 | b0126 | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | 0.964 |
cynS | cynT | b0340 | b0339 | Cyanate aminohydrolase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate. | 0.998 |
cynT | adhE | b0339 | b1241 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate. | Acetaldehyde dehydrogenase [acetylating]; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction; In the N-terminal section; belongs to the aldehyde dehydrogenase family. | 0.424 |
cynT | caiE | b0339 | b0035 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate. | Stimulator of CaiD and CaiB enzyme activities; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. | 0.589 |
cynT | can | b0339 | b0126 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to catalyze the hydration of carbon dioxide and thus prevent depletion of cellular bicarbonate. | Putative carbonic anhdrase; Belongs to the beta-class carbonic anhydrase family. | 0.943 |