STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yadEPutative polysaccharide deacetylase lipoprotein; Uncharacterized protein YadE (409 aa)    
Predicted Functional Partners:
yjaH
annotation not available
  
   
 0.848
yafL
Putative lipoprotein and c40 family peptidase; Probable endopeptidase YafL; Putative lipoprotein
   
  
 0.737
ybjT
Putative NAD(P)-binding protein YbjT; Putative enzyme; Not classified
      
 0.732
yfhL
Putative 4fe-4s cluster-containing protein yfhl; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
      
 0.703
pgaC
Poly-n-acetyl-d-glucosamine synthase subunit pgac; Probable N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide
 
  
 0.692
yadI
Putative pts enzyme iia component yadi; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
 
     0.684
ycaR
Peroxide and acid resistance protein, upf0434 family; Belongs to the UPF0434 family
    
 
 0.660
arnD
Putative 4-deoxy-4-formamido-l-arabinose-phosphoundecaprenol deformylase arnd; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (Probable)
      
 0.609
yebF
annotation not available
      
 0.577
arnF
Undecaprenyl-phosphate-alpha-L-Ara4N flippase - ArnF subunit; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane
  
  
 0.529
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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