STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yadEPutative polysaccharide deacetylase lipoprotein. (409 aa)    
Predicted Functional Partners:
yjaH
DUF1481 family putative lipoprotein.
      
 0.782
ybjT
Putative NAD-dependent oxidoreductase.
  
   
 0.652
yafL
Putative lipoprotein and C40 family peptidase; Putative lipoprotein.
      
 0.644
yadI
Putative PTS Enzyme IIA; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.
  
    0.635
ycaR
Peroxide and acid resistance protein, UPF0434 family; Belongs to the UPF0434 family.
      
 0.533
caiD
carnitinyl-CoA dehydratase; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.
      
 0.525
ycdZ
DUF1097 family inner membrane protein.
  
     0.513
nanT
Sialic acid transporter; Catalyzes the proton-dependent transport of sialic acid. Can transport the common sialic acid N-acetylneuraminic acid (Neu5Ac) and the related sialic acids N- glycolylneuraminic acid (Neu5Gc) and 3-keto-3-deoxy-D-glycero-D- galactonononic acid (KDN). Functions as a bidirectional transporter in vitro. Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
  
     0.508
arnD
Undecaprenyl phosphate-alpha-L-ara4FN deformylase; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (Probable).
      
 0.507
cadC
cadBA operon transcriptional activator; Required for Pcad induction, a promoter upstream of cadBA that is responsible for the pH-regulated expression of CadA and CadB. Probably acts as an activating transcription factor.
  
    0.496
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.