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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metNL-methionine/d-methionine abc transporter atp binding subunit; Part of the ABC transporter complex MetNIQ involved in methionine import Responsible for energy coupling to the transport system . It has also been shown to be involved in formyl-L-methionine transport (343 aa)    
Predicted Functional Partners:
metQ
L-methionine/d-methionine abc transporter membrane anchored binding protein; This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system
 0.999
metI
L-methionine/d-methionine abc transporter membrane subunit; Part of the binding-protein-dependent transport system for D- methionine and the toxic methionine analog alpha-methyl-methionine. Probably responsible for the translocation of the substrate across the membrane
 0.999
nlpA
D-methionine transport system substrate-binding protein; Lipoprotein-28
 
 0.976
btuC
Vitamin b12 transport system permease protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane
     
 0.941
btuD
Vitamin b12 transport system atp-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
 
  
0.924
msbA
Atp-binding cassette, subfamily b, bacterial msba; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
     
0.922
ugpA
Sn-glycerol 3-phosphate abc transporter membrane subunit ugpa; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane
     
 0.919
malF
Maltose/maltodextrin transport system permease protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane
     
 0.914
malK
Multiple sugar transport system atp-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system
  
  
0.912
fhuC
Iron(iii) hydroxamate abc transporter atp binding subunit; Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system
  
  
0.908
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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