STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yafLPutative lipoprotein and c40 family peptidase; Probable endopeptidase YafL; Putative lipoprotein (249 aa)    
Predicted Functional Partners:
rayT
Rayt rep element-mobilizing transposase; Transposase that is always flanked by repeated extragenic palindrome (REP) sequences, which are clustered in structures called bacterial interspersed mosaic elements (BIMEs). RayT catalyzes cleavage and recombination of BIMEs. Binds REP sequences and cleaves BIMEs both upstream and downstream of the REP sequence. Could be important in the creation of BIME variability and amplification
     
 0.882
ycgY
annotation not available
      
 0.830
ybeT
annotation not available
      
 0.828
yncH
annotation not available
      
 0.828
yebY
annotation not available
      
 0.788
yjaH
annotation not available
    
 
 0.752
yadE
Putative polysaccharide deacetylase lipoprotein; Uncharacterized protein YadE
   
  
 0.737
ycjO
Multiple sugar transport system permease protein; Probably part of the binding-protein-dependent transport system YcjNOP. Probably responsible for the translocation of the substrate across the membrane
      
 0.734
yiiR
annotation not available
      
 0.732
hyfJ
Putative processing element hydrogenase 4; Possible component of hydrogenase 4
      
 0.731
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.