STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
afuCCP4-6 prophage; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (348 aa)    
Predicted Functional Partners:
nikD
Nickel ABC transporter ATPase; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
 
 
 
0.942
sapD
Antimicrobial peptide ABC transporter ATPase; Part of a putrescine export transport system, does not play a role in resistance to antimicrobial peptides. Stimulates K(+)-uptake proteins TrkG and TrkH to import K(+), may act via ATP-binding rather than ATP hydrolysis.
 
 
 
0.930
fbaA
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
      
 0.916
mdlA
Putative multidrug ABC transporter ATPase; Protein involved in response to drug; Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
 
    
0.908
cydD
Glutathione/cysteine ABC transporter export permease/ATPase; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system.
 
   
 
0.907
cydC
Glutathione/cysteine ABC transporter export permease/ATPase; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system; Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3.A.1.129.1) family.
 
  
 
0.874
potB
Spermidine/putrescine ABC transporter permease; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 0.869
ybhS
Putative ABC transporter permease; Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably involved in the translocation of the substrate across the membrane. Belongs to the ABC-2 integral membrane protein family.
 
   
  0.863
potC
Spermidine/putrescine ABC transporter permease; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 0.857
potH
Putrescine ABC transporter permease; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 0.768
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.