STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yagKTo E.coli YfjJ (208 aa)    
Predicted Functional Partners:
yfjI
Uncharacterized protein YfjI; Phage or Prophage Related
  
     0.761
gtrS
Uncharacterized protein YfdI; Putative ligase
      
 0.732
yfjR
Uncharacterized HTH-type transcriptional regulator YfjR; Phage or Prophage Related
  
     0.728
yfjX
Belongs to the antirestriction protein family.
  
     0.715
yafX
Uncharacterized protein YafX; Phage or Prophage Related; Belongs to the antirestriction protein family
  
     0.709
ykfA
To E.coli YfjP and YeeP
  
     0.709
yafZ
Belongs to the UPF0380 family
  
     0.706
yfjQ
UPF0380 protein YfjQ; Phage or Prophage Related; Belongs to the UPF0380 family
  
     0.706
ykfI
Toxic component of a type IV toxin-antitoxin (TA) system . Acts as a toxin inhibitor that blocks cell division and cell elongation via FtsZ and possibly also MreB (although no interaction with MreB has been proven) . Overexpression results in inhibition of growth in liquid cultures and a decrease in colony formation (PubMed:14594833, PubMed:28257056, PubMed:28931012). These effects are overcome by concomitant expression of cognate antitoxin YafW, which leads to toxin loss by an unknown mechanism . Overexpression leads to formation of lemon-shaped cells and cell lysis; inactivated by ov [...]
  
     0.704
yfjP
To E.coli YkfA and YeeP
  
     0.704
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (5%) [HD]