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phoR protein (Escherichia coli K12 MG1655) - STRING interaction network
"phoR" - Phosphate regulon sensor protein PhoR in Escherichia coli K12 MG1655
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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phoRPhosphate regulon sensor protein PhoR; Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals (431 aa)    
Predicted Functional Partners:
phoB
Phosphate regulon transcriptional regulatory protein PhoB; This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (229 aa)
  0.999
phoU
Phosphate-specific transport system accessory protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. Encoded together with proteins of the phosphate-specific transport (Pst) system in the polycistronic pstSCAB-phoU operon. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. In this role, it may bind, possibly as a chaperone, to PhoR, PhoB or a PhoR-PhoB complex to promote dephosphorylation of phospho-PhoB, or inhibit formation of the PhoR-PhoB transitory complex. Is also part of complex networks important fo [...] (241 aa)
 
 
  0.991
phoA
Alkaline phosphatase; start codon corrected; Protein involved in phosphorus metabolic process; Belongs to the alkaline phosphatase family (471 aa)
   
 
  0.943
pstB
Phosphate import ATP-binding protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family (257 aa)
 
   
  0.923
pstS
Phosphate-binding protein PstS; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family (346 aa)
 
   
  0.887
pstC
Phosphate transport system permease protein PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane (319 aa)
 
   
  0.883
pstA
Phosphate transport system permease protein PstA; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane (296 aa)
 
   
  0.869
phoP
Transcriptional regulatory protein PhoP; Member of the two-component regulatory system PhoP/PhoQ involved in adaptation to low Mg(2+) environments and the control of acid resistance genes. In low periplasmic Mg(2+), PhoQ phosphorylates PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG). In high periplasmic Mg(2+), PhoQ dephosphorylates phospho-PhoP, resulting in the repression of PAG and may lead to expression of some PRG (By similarity). Mediates magnesium influx to the cytosol by activation of MgtA. Promotes expression of the [...] (223 aa)
 
     
  0.846
ompR
Transcriptional regulatory protein OmpR; The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the OmpR protein. As a multimer, it turns on the expression of the ompC gene; as a monomer, it turns on the expression of the ompF gene (239 aa)
 
 
 
  0.799
creB
Transcriptional regulatory protein CreB; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation (229 aa)
     
  0.787
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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