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glsA protein (Escherichia coli K12 MG1655) - STRING interaction network
"glsA" - Putative glutaminase in Escherichia coli K12 MG1655
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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glsAPutative glutaminase; Protein involved in cellular amino acid catabolic process (310 aa)    
Predicted Functional Partners:
gadB
Glutamate decarboxylase beta; Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria; Belongs to the group II decarboxylase family (466 aa)
 
  0.994
gadA
Glutamate decarboxylase alpha; Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria (466 aa)
 
  0.994
ybaT
Inner membrane transport protein YbaT; Probable amino-acid or metabolite transport protein (430 aa)
        0.983
gltB
Glutamate synthase [NADPH] large chain; Catalyzes the conversion of L-glutamine and 2- oxoglutarate into two molecules of L-glutamate (1486 aa)
   
 
  0.949
gadC
Probable glutamate/gamma-aminobutyrate antiporter; Involved in glutamate-dependent acid resistance. Imports glutamate inside the cell while simultaneously exporting to the periplasm the GABA produced by GadA and GadB. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Glutamate [...] (511 aa)
   
  0.949
putA
Bifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon; In the C-terminal section; belongs to the aldehyde dehydrogenase family (1320 aa)
     
 
  0.928
gltD
Glutamate synthase [NADPH] small chain; Catalyzes the conversion of L-glutamine and 2- oxoglutarate into two molecules of L-glutamate (472 aa)
     
 
  0.914
glnA
Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia (469 aa)
       
  0.912
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis; Belongs to the aspartate/glutamate racemases family (285 aa)
         
  0.911
carB
Carbamoyl-phosphate synthase large chain; Protein involved in arginine biosynthetic process and pyrimidine nucleotide biosynthetic process; Belongs to the CarB family (1073 aa)
     
 
  0.902
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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