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allR protein (Escherichia coli K12 MG1655) - STRING interaction network
"allR" - HTH-type transcriptional repressor AllR in Escherichia coli K12 MG1655
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Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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allRHTH-type transcriptional repressor AllR; Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region. Binding to DNA is abolished by glyoxylate (271 aa)    
Predicted Functional Partners:
allA
Ureidoglycolate lyase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the anaerobic utilization of allantoin as sole nitrogen source. Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate (160 aa)
 
     
  0.743
ascG
HTH-type transcriptional regulator AscG; Repressor of the asc operon. The cryptic operon is activated by the insertion of IS186 into the ascG gene (336 aa)
           
  0.680
hyi
Hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde). Does not catalyze the isomerization of D-fructose to D-glucose or that of D-xylulose to D-xylose. Also does not catalyze racemization of serine, alanine, glycerate or lactate (258 aa)
 
          0.670
gcl
Glyoxylate carboligase; Catalyzes the condensation of two molecules of glyoxylate to give 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (593 aa)
 
          0.659
rutR
HTH-type transcriptional regulator RutR; Master transcription regulator which represses the degradation of pyrimidines (rutABCDEFG) and purines (gcl operon) for maintenance of metabolic balance between pyrimidines and purines. It also regulates the synthesis of pyrimidine nucleotides and arginine from glutamine (carAB) and the supply of glutamate (gadABWX) (212 aa)
           
  0.620
tyrR
Transcriptional regulatory protein TyrR; Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalani [...] (513 aa)
           
  0.562
nemR
HTH-type transcriptional repressor NemR; Represses the transcription of the nemRA operon by binding to the nemR box (199 aa)
           
  0.552
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family (315 aa)
           
  0.499
mhpR
DNA-binding transcriptional activator MhpR; Activator of the mhpABCDFE operon coding for components of the 3-hydroxyphenylpropionate degradation pathway (277 aa)
   
 
 
  0.482
citB
Transcriptional regulatory protein DpiA; Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions. Regulates the transcription of citCDEFXGT, dpiAB, mdh and exuT. Binds specifically to the dpiB-citC intergenic region (226 aa)
           
  0.469
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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