STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfrBBacteriophage n4 receptor, inner membrane subunit; Required for bacteriophage N4 adsorption. May be a component of the phage receptor (745 aa)    
Predicted Functional Partners:
nfrA
Bacteriophage n4 receptor, outer membrane protein; (Microbial infection) Allows N4 phage attachment by binding to the viral non-contractile sheath protein
 
   
 0.994
ybcH
annotation not available
 
     0.973
wecB
Udp-n-acetylglucosamine 2-epimerase (non-hydrolysing); Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. Also involved in bacteriophage N4 adsorption
 
   
 0.891
damX
Cell division protein that binds to the septal ring; Non-essential cell division protein
   
 
 0.635
gspD
General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane. This subunit would form the outer membrane channel
   
 
  0.555
gspE
General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
     
  0.540
gspG
Pseudopilin, cryptic, general secretion pathway; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
     
  0.540
gspH
Putative general secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
     
  0.540
gspI
General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
     
  0.540
mdtO
Membrane translocase (mdr) of mdtnop efflux pump, pet family; Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride
  
     0.538
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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