Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| baeR | cusS | b2079 | b0570 | Member of the two-component regulatory system BaeS/BaeR which responds to envelope stress . Activates expression of periplasmic chaperone spy in response to spheroplast formation, indole and P pili protein PapG overexpression . Activates the mdtABCD and probably the CRISPR-Cas casABCDE-ygbT-ygbF operon | Copper-sensing histidine kinase in two-component regulatory system with cusr; Member of the two-component regulatory system CusS/CusR involved in response to copper and silver. Acts as a copper/silver ion sensor. Activates CusR by phosphorylation | 0.650 |
| cueO | cueR | b0123 | b0487 | Cuprous oxidase/multicopper oxidase with role in copper homeostasis; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm | Merr family transcriptional regulator, copper efflux regulator; Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations | 0.952 |
| cueO | cusA | b0123 | b0575 | Cuprous oxidase/multicopper oxidase with role in copper homeostasis; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm | Copper/silver efflux system, membrane component; Part of a cation efflux system that mediates resistance to copper and silver | 0.894 |
| cueO | cusB | b0123 | b0574 | Cuprous oxidase/multicopper oxidase with role in copper homeostasis; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm | Copper/silver efflux system, membrane fusion protein; Part of a cation efflux system that mediates resistance to copper and silver | 0.885 |
| cueO | cusC | b0123 | b0572 | Cuprous oxidase/multicopper oxidase with role in copper homeostasis; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm | Copper/silver efflux system, outer membrane component; Forms pores that allow passive diffusion of cations across the outer membrane. Part of a cation efflux system that mediates resistance to copper and silver. In pathogenic strains it allows the bacteria to invade brain microvascular endothelial cells (BMEC) thus allowing it to cross the blood-brain barrier and cause neonatal meningitis | 0.877 |
| cueO | cusF | b0123 | b0573 | Cuprous oxidase/multicopper oxidase with role in copper homeostasis; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm | Copper/silver export system periplasmic binding protein; Part of a cation efflux system that mediates resistance to copper and silver. Binds one copper per polypeptide | 0.885 |
| cueO | cusR | b0123 | b0571 | Cuprous oxidase/multicopper oxidase with role in copper homeostasis; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm | Two-component system, ompr family, copper resistance phosphate regulon response regulator cusr; Member of the two-component regulatory system CusS/CusR involved in response to copper and silver. Activates the expression of cusCFBA, hiuH and plasmid pRJ1004 gene pcoE in response to increasing levels of copper or silver ions. Can also increase the basal-level expression of copper resistance gene operon pcoABCD | 0.889 |
| cueO | cusS | b0123 | b0570 | Cuprous oxidase/multicopper oxidase with role in copper homeostasis; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm | Copper-sensing histidine kinase in two-component regulatory system with cusr; Member of the two-component regulatory system CusS/CusR involved in response to copper and silver. Acts as a copper/silver ion sensor. Activates CusR by phosphorylation | 0.887 |
| cueR | cueO | b0487 | b0123 | Merr family transcriptional regulator, copper efflux regulator; Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations | Cuprous oxidase/multicopper oxidase with role in copper homeostasis; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm | 0.952 |
| cueR | cusA | b0487 | b0575 | Merr family transcriptional regulator, copper efflux regulator; Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations | Copper/silver efflux system, membrane component; Part of a cation efflux system that mediates resistance to copper and silver | 0.819 |
| cueR | cusB | b0487 | b0574 | Merr family transcriptional regulator, copper efflux regulator; Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations | Copper/silver efflux system, membrane fusion protein; Part of a cation efflux system that mediates resistance to copper and silver | 0.803 |
| cueR | cusC | b0487 | b0572 | Merr family transcriptional regulator, copper efflux regulator; Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations | Copper/silver efflux system, outer membrane component; Forms pores that allow passive diffusion of cations across the outer membrane. Part of a cation efflux system that mediates resistance to copper and silver. In pathogenic strains it allows the bacteria to invade brain microvascular endothelial cells (BMEC) thus allowing it to cross the blood-brain barrier and cause neonatal meningitis | 0.783 |
| cueR | cusF | b0487 | b0573 | Merr family transcriptional regulator, copper efflux regulator; Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations | Copper/silver export system periplasmic binding protein; Part of a cation efflux system that mediates resistance to copper and silver. Binds one copper per polypeptide | 0.878 |
| cueR | cusR | b0487 | b0571 | Merr family transcriptional regulator, copper efflux regulator; Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations | Two-component system, ompr family, copper resistance phosphate regulon response regulator cusr; Member of the two-component regulatory system CusS/CusR involved in response to copper and silver. Activates the expression of cusCFBA, hiuH and plasmid pRJ1004 gene pcoE in response to increasing levels of copper or silver ions. Can also increase the basal-level expression of copper resistance gene operon pcoABCD | 0.891 |
| cueR | cusS | b0487 | b0570 | Merr family transcriptional regulator, copper efflux regulator; Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations | Copper-sensing histidine kinase in two-component regulatory system with cusr; Member of the two-component regulatory system CusS/CusR involved in response to copper and silver. Acts as a copper/silver ion sensor. Activates CusR by phosphorylation | 0.845 |
| cusA | cueO | b0575 | b0123 | Copper/silver efflux system, membrane component; Part of a cation efflux system that mediates resistance to copper and silver | Cuprous oxidase/multicopper oxidase with role in copper homeostasis; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm | 0.894 |
| cusA | cueR | b0575 | b0487 | Copper/silver efflux system, membrane component; Part of a cation efflux system that mediates resistance to copper and silver | Merr family transcriptional regulator, copper efflux regulator; Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations | 0.819 |
| cusA | cusB | b0575 | b0574 | Copper/silver efflux system, membrane component; Part of a cation efflux system that mediates resistance to copper and silver | Copper/silver efflux system, membrane fusion protein; Part of a cation efflux system that mediates resistance to copper and silver | 0.999 |
| cusA | cusC | b0575 | b0572 | Copper/silver efflux system, membrane component; Part of a cation efflux system that mediates resistance to copper and silver | Copper/silver efflux system, outer membrane component; Forms pores that allow passive diffusion of cations across the outer membrane. Part of a cation efflux system that mediates resistance to copper and silver. In pathogenic strains it allows the bacteria to invade brain microvascular endothelial cells (BMEC) thus allowing it to cross the blood-brain barrier and cause neonatal meningitis | 0.999 |
| cusA | cusF | b0575 | b0573 | Copper/silver efflux system, membrane component; Part of a cation efflux system that mediates resistance to copper and silver | Copper/silver export system periplasmic binding protein; Part of a cation efflux system that mediates resistance to copper and silver. Binds one copper per polypeptide | 0.999 |
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