node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
mrdA | mrdB | b0635 | b0634 | Penicillin-binding protein 2, transpeptidase involved in peptidoglycan synthesis; Catalyzes cross-linking of the peptidoglycan cell wall . Responsible for the determination of the rod shape of the cell . Is probably required for lateral peptidoglycan synthesis and maintenance of the correct diameter during lateral and centripetal growth | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation . Also required for the maintenance of the rod cell shape . Functions probably in conjunction with the penicillin-binding protein 2 (mrdA) | 0.999 |
mrdA | nadD | b0635 | b0639 | Penicillin-binding protein 2, transpeptidase involved in peptidoglycan synthesis; Catalyzes cross-linking of the peptidoglycan cell wall . Responsible for the determination of the rod shape of the cell . Is probably required for lateral peptidoglycan synthesis and maintenance of the correct diameter during lateral and centripetal growth | Nicotinic acid mononucleotide adenylyltransferase, nad(p)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) | 0.593 |
mrdA | rlmH | b0635 | b0636 | Penicillin-binding protein 2, transpeptidase involved in peptidoglycan synthesis; Catalyzes cross-linking of the peptidoglycan cell wall . Responsible for the determination of the rod shape of the cell . Is probably required for lateral peptidoglycan synthesis and maintenance of the correct diameter during lateral and centripetal growth | 23S rRNA m(3)Psi1915 pseudouridine methyltransferase, SAM-dependent; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. Specific for fully assembled 70S ribosomes | 0.973 |
mrdA | rlpA | b0635 | b0633 | Penicillin-binding protein 2, transpeptidase involved in peptidoglycan synthesis; Catalyzes cross-linking of the peptidoglycan cell wall . Responsible for the determination of the rod shape of the cell . Is probably required for lateral peptidoglycan synthesis and maintenance of the correct diameter during lateral and centripetal growth | Septal ring protein, suppressor of prc, minor lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides | 0.984 |
mrdA | rsfS | b0635 | b0637 | Penicillin-binding protein 2, transpeptidase involved in peptidoglycan synthesis; Catalyzes cross-linking of the peptidoglycan cell wall . Responsible for the determination of the rod shape of the cell . Is probably required for lateral peptidoglycan synthesis and maintenance of the correct diameter during lateral and centripetal growth | Ribosomal silencing factor rsfs; Functions as a ribosomal silencing factor. Addition to isolated ribosomal subunits partially inhibits their association, preventing translation. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8, preventing association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation | 0.877 |
mrdB | mrdA | b0634 | b0635 | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation . Also required for the maintenance of the rod cell shape . Functions probably in conjunction with the penicillin-binding protein 2 (mrdA) | Penicillin-binding protein 2, transpeptidase involved in peptidoglycan synthesis; Catalyzes cross-linking of the peptidoglycan cell wall . Responsible for the determination of the rod shape of the cell . Is probably required for lateral peptidoglycan synthesis and maintenance of the correct diameter during lateral and centripetal growth | 0.999 |
mrdB | nadD | b0634 | b0639 | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation . Also required for the maintenance of the rod cell shape . Functions probably in conjunction with the penicillin-binding protein 2 (mrdA) | Nicotinic acid mononucleotide adenylyltransferase, nad(p)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) | 0.563 |
mrdB | rlmH | b0634 | b0636 | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation . Also required for the maintenance of the rod cell shape . Functions probably in conjunction with the penicillin-binding protein 2 (mrdA) | 23S rRNA m(3)Psi1915 pseudouridine methyltransferase, SAM-dependent; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. Specific for fully assembled 70S ribosomes | 0.863 |
mrdB | rlpA | b0634 | b0633 | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation . Also required for the maintenance of the rod cell shape . Functions probably in conjunction with the penicillin-binding protein 2 (mrdA) | Septal ring protein, suppressor of prc, minor lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides | 0.988 |
mrdB | rsfS | b0634 | b0637 | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation . Also required for the maintenance of the rod cell shape . Functions probably in conjunction with the penicillin-binding protein 2 (mrdA) | Ribosomal silencing factor rsfs; Functions as a ribosomal silencing factor. Addition to isolated ribosomal subunits partially inhibits their association, preventing translation. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8, preventing association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation | 0.824 |
nadD | mrdA | b0639 | b0635 | Nicotinic acid mononucleotide adenylyltransferase, nad(p)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) | Penicillin-binding protein 2, transpeptidase involved in peptidoglycan synthesis; Catalyzes cross-linking of the peptidoglycan cell wall . Responsible for the determination of the rod shape of the cell . Is probably required for lateral peptidoglycan synthesis and maintenance of the correct diameter during lateral and centripetal growth | 0.593 |
nadD | mrdB | b0639 | b0634 | Nicotinic acid mononucleotide adenylyltransferase, nad(p)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation . Also required for the maintenance of the rod cell shape . Functions probably in conjunction with the penicillin-binding protein 2 (mrdA) | 0.563 |
nadD | rlmH | b0639 | b0636 | Nicotinic acid mononucleotide adenylyltransferase, nad(p)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) | 23S rRNA m(3)Psi1915 pseudouridine methyltransferase, SAM-dependent; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. Specific for fully assembled 70S ribosomes | 0.819 |
nadD | rlpA | b0639 | b0633 | Nicotinic acid mononucleotide adenylyltransferase, nad(p)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) | Septal ring protein, suppressor of prc, minor lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides | 0.562 |
nadD | rpmA | b0639 | b3185 | Nicotinic acid mononucleotide adenylyltransferase, nad(p)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) | Large subunit ribosomal protein l27; 50S ribosomal protein L27; Protein involved in structural constituent of ribosome and translation | 0.556 |
nadD | rsfS | b0639 | b0637 | Nicotinic acid mononucleotide adenylyltransferase, nad(p)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) | Ribosomal silencing factor rsfs; Functions as a ribosomal silencing factor. Addition to isolated ribosomal subunits partially inhibits their association, preventing translation. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8, preventing association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation | 0.863 |
rlmH | mrdA | b0636 | b0635 | 23S rRNA m(3)Psi1915 pseudouridine methyltransferase, SAM-dependent; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. Specific for fully assembled 70S ribosomes | Penicillin-binding protein 2, transpeptidase involved in peptidoglycan synthesis; Catalyzes cross-linking of the peptidoglycan cell wall . Responsible for the determination of the rod shape of the cell . Is probably required for lateral peptidoglycan synthesis and maintenance of the correct diameter during lateral and centripetal growth | 0.973 |
rlmH | mrdB | b0636 | b0634 | 23S rRNA m(3)Psi1915 pseudouridine methyltransferase, SAM-dependent; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. Specific for fully assembled 70S ribosomes | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation . Also required for the maintenance of the rod cell shape . Functions probably in conjunction with the penicillin-binding protein 2 (mrdA) | 0.863 |
rlmH | nadD | b0636 | b0639 | 23S rRNA m(3)Psi1915 pseudouridine methyltransferase, SAM-dependent; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. Specific for fully assembled 70S ribosomes | Nicotinic acid mononucleotide adenylyltransferase, nad(p)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) | 0.819 |
rlmH | rlpA | b0636 | b0633 | 23S rRNA m(3)Psi1915 pseudouridine methyltransferase, SAM-dependent; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. Specific for fully assembled 70S ribosomes | Septal ring protein, suppressor of prc, minor lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides | 0.869 |