STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
djlBUncharacterized J domain-containing protein DjlB; Putative enzyme of polynucleotide modification; Protein involved in protein folding (475 aa)    
Predicted Functional Partners:
ybeR
DUF1266 domain-containing protein YbeR; To E.coli YbeU
 
    0.967
yhdV
annotation not available
      
 0.900
hscC
Hsp70 family chaperone Hsc62; Probable chaperone. Has ATPase activity. Not stimulated by DnaJ
 
 0.859
ybeU
DUF1266 domain-containing protein YbeU; To E.coli YbeR
 
    0.813
yegD
Hsp70 chaperone family protein; Belongs to the heat shock protein 70 family
   
 0.807
nrfF
Heme lyase (nrfefg) for insertion of heme into c552, subunit nrff; Not required for the biosynthesis of any of the c-type cytochromes. Possible subunit of a heme lyase
      
 0.790
yjcF
annotation not available
  
     0.773
flk
Putative flagella assembly protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion (T3S) system. Plays a role in hindering to flip the flagellar T3S specificity switch from the rod and hook-type substrates to filament-type substrates prior to hook-basal body (HBB) completion possibly by preventing interaction of FliK with FlhB (By similarity)
  
   
 0.765
recE
Rac prophage; exonuclease viii, ds dna exonuclease, 5' --> 3' specific; Is involved in the RecE pathway of recombination. Catalyzes the degradation of double-stranded DNA. Acts progressively in a 5' to 3' direction, releasing 5'-phosphomononucleotides. Has a strong preference for linear duplex substrate DNA and appears to be unable to initiate degradation from single-stranded breaks in DNA
  
    0.755
ymiA
annotation not available
      
 0.739
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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