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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kdpAPotassium-transporting atpase potassium-binding subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit binds and transports the potassium across the cytoplasmic membrane (557 aa)    
Predicted Functional Partners:
kdpD
Fused sensory histidine kinase in two-component regulatory system with kdpe: signal sensing protein; Member of the two-component regulatory system KdpD/KdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates KdpE in response to environmental signals
 
 0.999
kdpC
K(+) transporting p-type atpase subunit kdpc; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP- hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex
 0.999
kdpB
Potassium-transporting atpase atp-binding subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit is responsible for energy coupling to the transport system
 0.999
kdpF
K(+) transporting p-type atpase subunit kdpf; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm . This subunit may be involved in stabilization of the complex
   
 0.999
kdpE
Two-component system, ompr family, kdp operon response regulator kdpe; Member of the two-component regulatory system KdpD/KdpE involved in the regulation of the kdp operon
  
 0.997
kup
Kup system potassium uptake protein; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium
     
 0.908
metQ
L-methionine/d-methionine abc transporter membrane anchored binding protein; This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system
    
  0.905
potG
Part of the binding-protein-dependent transport system for putrescine. Probably responsible for energy coupling to the transport system
    
  0.905
potA
Spermidine preferential abc transporter atp binding subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system
    
  0.905
ugpC
Sn-glycerol 3-phosphate transport system atp-binding protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system (Probable). Can also transport glycerophosphoryl diesters
    
  0.905
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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