node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acrA | acrB | b0463 | b0462 | Multidrug efflux pump membrane fusion lipoprotein acra; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates. This subunit may act as an adapter protein that links AcrB and TolC stably together. It is elongated in shape, being long enough to span the periplasm | Multidrug efflux pump rnd permease acrb; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates | 0.999 |
acrA | acrZ | b0463 | b0762 | Multidrug efflux pump membrane fusion lipoprotein acra; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates. This subunit may act as an adapter protein that links AcrB and TolC stably together. It is elongated in shape, being long enough to span the periplasm | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | 0.994 |
acrA | tolC | b0463 | b3035 | Multidrug efflux pump membrane fusion lipoprotein acra; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates. This subunit may act as an adapter protein that links AcrB and TolC stably together. It is elongated in shape, being long enough to span the periplasm | Outer membrane channel, which is required for the function of several efflux systems such as AcrAB-TolC, AcrEF-TolC, EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. TolC is also involved in import of colicin E1 into the cells | 0.999 |
acrB | acrA | b0462 | b0463 | Multidrug efflux pump rnd permease acrb; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates | Multidrug efflux pump membrane fusion lipoprotein acra; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates. This subunit may act as an adapter protein that links AcrB and TolC stably together. It is elongated in shape, being long enough to span the periplasm | 0.999 |
acrB | acrZ | b0462 | b0762 | Multidrug efflux pump rnd permease acrb; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | 0.982 |
acrB | tolC | b0462 | b3035 | Multidrug efflux pump rnd permease acrb; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates | Outer membrane channel, which is required for the function of several efflux systems such as AcrAB-TolC, AcrEF-TolC, EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. TolC is also involved in import of colicin E1 into the cells | 0.999 |
acrZ | acrA | b0762 | b0463 | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | Multidrug efflux pump membrane fusion lipoprotein acra; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates. This subunit may act as an adapter protein that links AcrB and TolC stably together. It is elongated in shape, being long enough to span the periplasm | 0.994 |
acrZ | acrB | b0762 | b0462 | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | Multidrug efflux pump rnd permease acrb; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates | 0.982 |
acrZ | cydX | b0762 | b4515 | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | Cytochrome d (bd-i) ubiquinol oxidase subunit x; Required for correct functioning of cytochrome bd-I oxidase. This protein and AppX may have some functional overlap | 0.813 |
acrZ | holE | b0762 | b1842 | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | Dna polymerase iii subunit theta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity | 0.760 |
acrZ | tolC | b0762 | b3035 | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | Outer membrane channel, which is required for the function of several efflux systems such as AcrAB-TolC, AcrEF-TolC, EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. TolC is also involved in import of colicin E1 into the cells | 0.968 |
acrZ | yecF | b0762 | b1915 | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | annotation not available | 0.750 |
acrZ | yhhL | b0762 | b3466 | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | annotation not available | 0.744 |
acrZ | yniB | b0762 | b1726 | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | annotation not available | 0.746 |
acrZ | yoaK | b0762 | b4676 | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | annotation not available | 0.780 |
acrZ | yqcG | b0762 | b4682 | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | annotation not available | 0.781 |
cydX | acrZ | b4515 | b0762 | Cytochrome d (bd-i) ubiquinol oxidase subunit x; Required for correct functioning of cytochrome bd-I oxidase. This protein and AppX may have some functional overlap | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | 0.813 |
cydX | yoaK | b4515 | b4676 | Cytochrome d (bd-i) ubiquinol oxidase subunit x; Required for correct functioning of cytochrome bd-I oxidase. This protein and AppX may have some functional overlap | annotation not available | 0.605 |
holE | acrZ | b1842 | b0762 | Dna polymerase iii subunit theta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity | Acrab-tolc efflux pump accessory protein, membrane-associated; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export | 0.760 |
holE | yecF | b1842 | b1915 | Dna polymerase iii subunit theta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity | annotation not available | 0.742 |