STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybhSABC-2 type transport system permease protein; Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably involved in the translocation of the substrate across the membrane (377 aa)    
Predicted Functional Partners:
ybhF
ABC-2 type transport system ATP-binding protein; Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably responsible for energy coupling to the transport system
 0.998
ybhR
ABC-2 type transport system permease protein; Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably involved in the translocation of the substrate across the membrane
 
 
0.990
ybhG
Putative membrane fusion protein (mfp) component of efflux pump, membrane anchor; Could be involved in the sensitivity control to chloramphenicol
   0.987
ybiH
Tetr/acrr family transcriptional regulator, regulator of cefoperazone and chloramphenicol sensitivity; Regulates transcription of the cecR-ybhGFSR operon and the rhlE gene, which altogether are involved in the control of sensitivity to cefoperazone and chloramphenicol. Represses the cecR-ybhGFSR operon and activates the rhlE operon. Acts by binding to a palindromic sequence within the intergenic spacer located between these two divergently transcribed operons
 
    0.934
yhiI
Putative membrane fusion protein (mfp) of efflux pump; Uncharacterized protein YhiI; Putative membrane protein
   0.733
yaiZ
annotation not available
      
 0.731
rbbA
Ribosome-associated atpase: atp-binding protein/atp-binding membrane protein; Exhibits an intrinsic ATPase activity that is stimulated by both 70S ribosomes and 30S ribosomal subunits. Could be involved in protein-chain elongation and in release of deacyl-tRNA from ribosomes after peptide bond synthesis. Stimulates the synthesis of polyphenylalanine in vitro
 
 
 
0.660
yhhJ
ABC-2 type transport system permease protein; Inner membrane transport permease YhhJ; Putative transporter
 
  
 
0.643
xylE
Mfs transporter, sp family, xylose:h+ symportor; Uptake of D-xylose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Glucose is not transported, but can compete for xylose binding sites and can inhibit xylose transport (in vitro)
   
 
 0.628
ydhU
Putative cytochrome b subunit of ydhyvwxut oxidoreductase complex; Putative cytochrome YdhU; Putative enzyme; Not classified
      
 0.619
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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