STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cydDGlutathione/cysteine abc transporter export permease/atpase; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (588 aa)    
Predicted Functional Partners:
cydC
Glutathione/cysteine abc transporter export permease/atpase; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system
 
0.993
cydB
Cytochrome bd-i ubiquinol oxidase subunit ii; A terminal oxidase that produces a proton motive force by the vectorial transfer of protons across the inner membrane. It is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at low aeration. Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O, transferring 1 proton/electron
 
 
 0.968
cydA
Cytochrome bd-i ubiquinol oxidase subunit i; A terminal oxidase that produces a proton motive force by the vectorial transfer of protons across the inner membrane. It is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at low aeration. Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O, transferring 1 proton/electron
 
 
 0.938
trxB
Thioredoxin reductase, fad/nad(p)-binding; Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
     
 0.857
proW
Glycine betaine/proline transport system permease protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake Probably responsible for the translocation of the substrate across the membrane (Probable)
     
 0.780
cbdB
Cytochrome bd-ii ubiquinol oxidase subunit ii; A terminal oxidase that catalyzes quinol-dependent, Na(+)- independent oxygen uptake. Prefers menadiol over other quinols although ubiquinol was not tested . Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O, transferring 1 proton/electron
 
 
 0.763
msbA
Atp-binding cassette, subfamily b, bacterial msba; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
 
 
0.762
metN
L-methionine/d-methionine abc transporter atp binding subunit; Part of the ABC transporter complex MetNIQ involved in methionine import Responsible for energy coupling to the transport system . It has also been shown to be involved in formyl-L-methionine transport
  
 
0.742
proV
Glycine betaine/proline abc transporter periplasmic binding protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake Probably responsible for energy coupling to the transport system (Probable)
 
  
0.742
fhuB
Iron(iii) hydroxamate abc transporter membrane subunit; Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane
    
 0.738
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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