STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycaPannotation not available (230 aa)    
Predicted Functional Partners:
ycaN
Putative lysr-type transcriptional regulator ycan; Belongs to the LysR transcriptional regulatory family
      
 0.909
ycaO
Ribosomal protein s12 methylthiotransferase accessory factor ycao; Involved in beta-methylthiolation of ribosomal protein S12
     
 0.871
hcaF
Putative 3-phenylpropionate/cinnamate dioxygenase subunit beta; Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively
      
 0.670
yciE
annotation not available
 
    0.542
yciF
Putative rubrerythrin/ferritin-like metal-binding protein; Protein YciF; Putative structural proteins
 
    0.539
sodC
Superoxide dismutase, cu, zn, periplasmic; Destroys radicals which are normally produced within the cells and which are toxic to biological systems
  
   0.524
katE
Catalase hpii, heme d-containing; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide
 
    0.522
otsB
trehalose-6-phosphate phosphatase, biosynthetic; Removes the phosphate from trehalose 6-phosphate (Tre6P) to produce free trehalose. Also catalyzes the dephosphorylation of glucose-6-phosphate (Glu6P) and 2-deoxyglucose-6-phosphate (2dGlu6P)
 
    0.503
serC
3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. Is involved in both pyridoxine and serine biosynthesis
       0.497
yciG
Uncharacterized protein; Belongs to the con-10 family
  
    0.488
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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