STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycaPUPF0702 family putative inner membrane protein. (230 aa)    
Predicted Functional Partners:
ycaN
Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family.
      
 0.740
yciF
Putative structural proteins.
 
    0.709
ycaO
Ribosomal protein S12 methylthiotransferase accessory factor; Involved in beta-methylthiolation of ribosomal protein S12.
     
 0.703
ybdR
Putative oxidoreductase.
  
    0.685
yhcO
Putative barnase inhibitor; Belongs to the barstar family.
   
    0.678
ybiO
Mechanosensitive channel protein, intermediate conductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Belongs to the MscS (TC 1.A.23) family.
  
  
 0.656
yfdQ
CPS-53 (KpLE1) prophage; uncharacterized protein.
      
 0.643
ydbD
PF10971 family putative periplasmic methylglyoxal resistance protein; To E.coli YkiA.
      
 0.624
yghA
Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.592
ybiV
Sugar phosphatase; Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of ribose-5-phosphate, glucose-6-phosphate, fructose-1- phosphate, acetyl-phosphate, glycerol-1-phosphate, glycerol-2- phosphate, 2-deoxy-glucose-6-phosphate, mannose-6-phosphate and fructose-6-phosphate. Appears to have a low level of phosphotransferase activity using monophosphates as the phosphate donor. Belongs to the HAD-like hydrolase superfamily. Cof family. SupH subfamily.
      
 0.505
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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