STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pqiCIntermembrane transport lipoprotein pqic; Component of a transport pathway that contributes to membrane integrity (187 aa)    
Predicted Functional Partners:
pqiB
Paraquat-inducible, soxrs-regulated mce domain protein; Paraquat-inducible protein B; Phenotype; Not classified; Belongs to the PqiB family
  
 0.999
pqiA
Paraquat-inducible, soxrs-regulated inner membrane protein; Component of a transport pathway that contributes to membrane integrity
  
 0.986
yebS
Intermembrane transport protein yebs; Component of a transport pathway that contributes to membrane integrity
 
  
 0.891
yebT
Intermembrane transport protein yebt; Component of a transport pathway that contributes to membrane integrity . May directly span the intermembrane space, facilitating the transport of substrates across the periplasm (Probable)
 
  
 0.889
ytcA
annotation not available
      
 0.731
ybfP
Uncharacterized lipoprotein YbfP; Putative pectinase
      
 0.697
rlmL
23S rRNA (guanine2445-N2)-methyltransferase / 23S rRNA (guanine2069-N7)-methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Methylation occurs before assembly of 23S rRNA into 50S subunits
       0.684
uup
Probably plays a role in ribosome assembly or function; overexpression suppresses cold-sensitive growth of a bipA deletion (Probable). May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA at Holliday junctions. May be involved in the correct segregation of nucleoids . Has ATPase activity, binds DNA non-sequence specifically; the presence of DNA does not change the ATPase activity . Mutations in this gene cause an increase in RecA-independent precise excision of transposons and insertion elements, and also red [...]
      0.677
ysaB
annotation not available
      
 0.677
yfiM
annotation not available
      
 0.641
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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